Researchers advise that people who suffer from epilepsy or seizures should ask for professional insight first before using binaural beats. Pregnant women are also advised to seek the advice of their physicians. However, I haven’t heard anything about binaural beats impacting those who have had heart attacks negatively. That being said, I encourage you to do extra research.
Controlled or pre/post studies of the effects of BWE using auditory or visual stimulation were eligible for inclusion, provided pulses of light or tone were delivered at frequencies hypothesised to have a beneficial effect or in line with a protocol addressing clinical outcomes. Studies were required to report clinical or psychological outcomes (measured using standard methods or as deemed appropriate by peer review) and to report statistical analysis. Studies of outcomes such as electroencephalogram (EEG) response or neurotransmitter levels were not eligible. Case studies were excluded.
A popular opinion in the brainwave entrainment community is that listening to isochronic tones without music produces a much stronger effect.  However, in the study by Doherty, Cormac. “A comparison of alpha brainwave entrainment, with and without musical accompaniment” (2014),  it was concluded that brainwave entrainment was equally effective for isochronic tones, both with and without music.
Entrainment is a principle of physics which appears in biology, chemistry, neurology, medicine, astronomy etc. It is defined as the synchronization of two or more rhythmic cycles. In the seventeenth century, Dutch scientist Christian Huygens found out that by placing two unsynchronized clocks side by side on a wall, they would slowly synchronize to each other in a very accurate way. The clocks were the first example of spontaneous synchronization, a phenomenon found throughout nature from cells to the Solar System.
There are general recommendations for stress management that can be applied in most situations. However, keep in mind that there are individual differences and preferences, so a “cookie cutter” approach should be avoided when making recommendations. A comprehensive stress management program will include specific techniques prescribed on an individual basis, but general stress management recommendations are presented in Table 2.
Binaural beats are created from two different continuous tones, which when sent separately to each ear create a single beat inside your head. Isochronic tones are basically a single tone which is switched on and off at regular intervals. Imagine a single continuous tone playing on a stereo system and you’ve got your hand on the volume switch. Then once per second, you turn the volume off for half a second and keep doing that every second. For half a second the volume is off, for the other half a beat waveform is formed. The beat is cycling once per second per second, i.e. at a rate of 1Hz.
Writing or talking about the things that prey on you—in a diary, with friends, in a support group or even a home computer file—helps you feel less alone and helpless. One study, published in The Journal of the American Medical Association, looked at people who had either rheumatoid arthritis or asthma— conditions known to be stress-sensitive. One group chronicled in a perfunctory manner the things they did each day. The other group was asked to write daily about what it was like, including fears and pain, to have their disease. What researchers found: People who wrote at length about their feelings had far fewer episodes of their illness.
There are five main categories of brainwave frequencies: Gamma (40Hz+), Beta (13 – 40Hz), Alpha (7 – 13Hz), Theta (4 – 7Hz), and Delta (<4Hz). Each category is associated with a different state of mind; so, for example, when you’re in a peak state of performance, your brain produces Alpha Waves, and when you’re in a deep sleep, your brain produces Delta Waves.
Set aside time in your daily schedule. If possible, schedule a set time once or twice a day for your practice. If your schedule is already packed, remember that many relaxation techniques can be practiced while performing other tasks. Try meditating while commuting on the bus or train, taking a yoga or tai chi break at lunchtime, or practicing mindful walking while exercising your dog.

♥ Taking the 16 HZ setting and combining it with a playlist of chilled out deadmau5 songs produces interesting effects, my right arm slowly began tingling and I eventually became rather focused on the task at hand. To be honest, although I don't go in for placebo and homeopathic remedies, the feeling I received from this combo made me feel... Alive... For the first time in a long time. It was nice.
When signals of two different frequencies are presented, one to each ear, the brain detects phase differences between these signals. "Under natural circumstances a detected phase difference would provide directional information. The brain processes this anomalous information differently when these phase differences are heard with stereo headphones or speakers. A perceptual integration of the two signals takes place, producing the sensation of a third "beat" frequency. The difference between the signals waxes and wanes as the two different input frequencies mesh in and out of phase. As a result of these constantly increasing and decreasing differences, an amplitude-modulated standing wave -the binaural beat- is heard. The binaural beat is perceived as a fluctuating rhythm at the frequency of the difference between the two auditory inputs. Evidence suggests that the binaural beats are generated in the brainstem's superior olivary nucleus, the first site of contra-lateral integration in the auditory system (Oster, 1973). Studies also suggest that the frequency-following response originates from the inferior colliculus (Smith, Marsh, & Brown, 1975)" (Owens & Atwater, 1995). This activity is conducted to the cortex where it can be recorded by scalp electrodes.  
Why is exposure to these soundwaves helpful to sleep and relaxation? Science shows that exposure to binaural beats can create changes in the brain’s degree of arousal. Listening to these sounds that create a low-frequency tone, research indicates, triggers a slow-down to brainwave activity—and that may help you relax, lower your anxiety, and can make it easier for you to fall asleep and sleep more soundly.
Most capsules either contain powdered, dry herbs, or a tiny bit of liquid extract (gel caps). Tablets are powdered herbs that are held together by pressure and other chemicals. The beauty of liquid extracts, or "tinctures," is that they absorb quickly and the body receives the full benefit of the plant in a very bio-available solution. Liquids also allow you to customize your serving freely so you can best meet your needs at the time. Liquids are inexpensive and easy to swallow. The droppers and pump top dispensers are also convenient for when you're on the go.
But the notion of changing brain waves is a very appealing one, from a marketing stand point. People can visualize brain waves and we like synchrony. Also, in the computer age, we understand the notion of “programming.” We also have been prepped for the future by movies such as The Matrix, where people could master Kung Fu in minutes by simply “downloading” the knowledge. This gives the whole notion a superficial plausibility. But the science just isn’t there.
Consider the following analogy. Imagine a ballroom full of people dancing together. When the music changes to a faster tempo, the dancers move faster in response to this. When a slower piece of music is played, the dancers’ rhythm slows down as well. In a similar way, the frequency of your brain will change in response to the frequency of the binaural beat that it is exposed to. For example, a person who is in a state of very deep meditation may have a dominant brainwave frequency of 5 hertz, so by listening to a binaural beat with a frequency of 5 hertz you can entrain your own brainwaves to a similar state.
There isn’t really a one-size-fits-all track or frequency range which is right for all kids while doing homework. So that does make it difficult to recommend one thing in particular, and why I have a number of tracks for studying and focus. If they have already learnt and understood the information, but are just trying to commit it to memory for a test, then I would recommend an alpha track, like the Memorization Study Aid product I have with the 10.4Hz frequency you referred to. If they are still trying to fully understand what is being taught in a workbook, then I would recommend a track that is mainly beta frequencies, like my Study Focus tracks. In the middle, I have a number of tracks which use a combination of beta and alpha wave frequencies, like Study Booster, Study Enhancer and Cognition Enhancer. The last 3 use similar frequencies but deliver the tones and brainwave entrainment effects in different ways. As we are all wired a little differently it does sometimes take a bit of trial and error, to see what method or frequency range works best for the individual. These types of tracks are made for a general audience. In an ideal world, you would hook up to an EEG and see in real time exactly what a person responds to best, depending on the goal and current state of mind.
You may recognize the "binaural recording" from ASMR, where the technique is often used. This explains why, if you search for "binaural" on YouTube, you get a mixture of two entirely different kinds of results: binaural beats and binaural ASMR recordings. It gets especially confusing in that there's some questionable and/or unexplored science surrounding each one.

By the 1980s, entrainment technology had merged with advancements in microelectronics technology, making it possible to develop even more sophisticated audio and visual brainwave entrainment products for the marketplace. In the last two decades, a number of scientific studies have reported brainwave entrainment as an effective remedy for ADD, academic learning problems, and improving memory and cognition.
Thanks to e-mail, cell phones, and BlackBerrys, it seems like your job never ends. The increasingly blurry boundaries between work and home life leave us with less downtime than ever before (and in some cases, no downtime!). Advances in technology are a leading source of chronic stress, putting many of us in a constant state of alert. Not to mention the effect it has on family ties. A recent study published in the Journal of Marriage and Family found a link between the use of cell phones and pagers at home and increased stress, which spills over into family life. To make technology work for you, screen calls with caller ID or, better yet, limit your cell phone and e-mail use to working hours only. Can't kick the BlackBerry habit? Set a regular time you'll check it in the evening (say, after dinner), so you're not constantly disrupting home life to keep tabs on work. (The one exception: using your device to breathe with this anxiety-reducing GIF.)
Although getting organized and staying organized is not often thought of as a stress management technique per se, this is an activity that can reduce the stress you face in your life, and can even be calming as you are engaged in the act. (See how cleaning can be a stress reliever in itself.) By working through the clutter of your life, you can eliminate those energy drains that can make you feel like you're 'being pecked to death by ducks' and reserve that energy for dealing with life's more important challenges. Read more on being organized and eliminating extra stress from your life. 
Resonant entrainment of oscillating systems is a well-understood principle within the physical sciences. If a tuning fork designed to produce a frequency of 440 Hz is struck (causing it to oscillate) and then brought into the vicinity of another 440 Hz tuning fork, the second tuning fork will begin to oscillate. The first tuning fork is said to have entrained the second or caused it to resonate. The physics of entrainment apply to bio-systems as well. Of interest here are the electromagnetic brain waves. The electrochemical activity of the brain results in the production of electromagnetic wave forms which can be objectively measured with sensitive equipment. Brain waves change frequencies based on neural activity within the brain. Because neural activity is electrochemical, brain function can be modified through the introduction of specific chemicals (drugs), by altering the brain's electromagnetic environment through induction, or through resonant entrainment techniques.
The brain is composed of millions of specialized cells called neurons. Neurons send signals to other neurons using electro-chemical messengers called neuro-transmitters that attach to receiving sites located on the neurons themselves. There is a space between the end of the neuron and the receptor called the synaptic gap. As neuro-transmitter chemicals move across this gap, a small electrical charge is created. 
Listening to brainwave entrainment music will provide you with the benefits of a formal meditation practice. It will improve your mental clarity, your creativity and your ability to learn and to concentrate. It will bring you peace of mind and emotional stability. It is also one of the most powerful natural ways to cure insomnia and can dramatically improve the quality of your sleep.
Thanks for the reply. I am now clearer on ‘what’ is heard. Can you expand or point me in direction ..a bit more about ‘pitch frequency’ and frequency spoken about and what exactly is the difference ..and how we use the higher pitch frequencies to ‘hear’ or become aware of them? Would you only pick up the low freq on a EEG?. sorry for being pedantic ..it still does not clear up split isochronics and possibly creating same situation as binaural beats..
The objectives and inclusion criteria of the review were clear. Relevant sources were searched for studies, although the restriction to published studies in English meant that the review was prone to publication and language biases. The authors did not state whether steps were taken to minimise the risk of bias and error in the processes of study selection and data extraction (for example, by having more than one reviewer independently make decisions). The authors mentioned which studies were blinded, but it did not appear that study validity was systematically assessed, which made it difficult to judge the reliability of the review findings. The decision to combine studies by narrative synthesis appeared appropriate given the strong clinical heterogeneity between the studies, but the authors failed to quantify the size or statistical significance of the findings reported. The evidence presented appeared to justify the authors’ conclusions that further research was justified, but in view of the dearth of good-quality evidence and problems with methodology and reporting in the review, the conclusions regarding efficacy did not appear reliable.
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