Regarding split hemisphere isochronic tones. Think of this as two separate isochronic tones tracks playing independently of each other, one playing in one ear and the other one in the opposite ear. Better still, imagine someone playing and recording a drum beat at a rate of 5 taps per second (5Hz – 5 cycles per second). Then a separate recording of a drum beat is made at a rate of 10 taps per second (10 Hz). You then make an audio track where the left ear/channel hears the 5 drum beats recording and the right ear/channel hears the 10 beat recording. With headphones on, each ear can only hear each respective drum beat and not the other. So you are hearing two different beat recordings at the same time, but it’s different in each ear. A split hemisphere isochronic tones track works just the same. You hear two beats at the same time, not two tones as with binaural beats that create a single beat, but two different speeds of beats in each ear. This is what enables you to stimulate and influence each side of the brain with a different frequency of beat. Binaural beats can only stimulate and influence a whole brain effect using a single beat.
Gamma waves are the fastest brainwave frequency range. Gamma brain waves are believed to link and process information from all other parts of the brain. A high amount of gamma wave activity in the brain is associated with intelligence, compassion, focus and feelings of happiness. High levels of gamma brain waves have also been linked to improved memory and an increased sensitivity to sensory input. Low amounts of gamma brainwave activity have been linked to learning difficulties, poor memory and impaired mental processing.
Generally speaking, the brain will usually entrain to the strongest stimulus which would be isochronic tones over binaural beats. So when you see people add binaural beats at a different frequency to the isochronic tones, that would not produce additional brainwave entrainment at another frequency. If they are both at the same frequency I haven’t seen any research to indicate whether that would be beneficial or not, but my belief is that it would weaken the potential for entrainment. When you look at the waveform of an isochronic tone there is a distinct empty space between each beat, making it very pronounced and effective. When you add binaural beats at the same frequency it looks like this: The depth of the waveform is now half as deep and less effective. This is before the binaural beats are formed inside your head, where the waveform is hard to determine and measure. From listening to that type of combination the beats sound much less pronounced, which has to make them much less effective in terms of a brainwave entrainment stimulus, compared to isochronic tones on their own.
“When you play two separate frequencies in each ear, say 140 Hz and 149 Hz, the difference in frequency is 9 Hz. Your brain compensates for this difference, and a third tone of 9 Hz is experienced,” says Niraj Naik, founder of Trpynaural, a resource for binaural tracks. “This will result in your brain being raised or lowered and tuned into the desired frequency. This is how binaural beats are produced.”
The functional role of neural oscillations is still not fully understood;[6] however they have been shown to correlate with emotional responses, motor control, and a number of cognitive functions including information transfer, perception, and memory.[7][8][9] Specifically, neural oscillations, in particular theta activity, are extensively linked to memory function, and coupling between theta and gamma activity is considered to be vital for memory functions, including episodic memory.[10][11][12]