I have a strange reaction to Binaural beats, as well as isochronic beats, and anything similar. After listening, I often feel vey fatigued, nauseous, and sometimes quite depressed. This effect can last a few days. So I stay away from it now, as well as guided meditations that have such beats in the background. Have you heard of this kind of reaction before?

Regarding split hemisphere isochronic tones. Think of this as two separate isochronic tones tracks playing independently of each other, one playing in one ear and the other one in the opposite ear. Better still, imagine someone playing and recording a drum beat at a rate of 5 taps per second (5Hz – 5 cycles per second). Then a separate recording of a drum beat is made at a rate of 10 taps per second (10 Hz). You then make an audio track where the left ear/channel hears the 5 drum beats recording and the right ear/channel hears the 10 beat recording. With headphones on, each ear can only hear each respective drum beat and not the other. So you are hearing two different beat recordings at the same time, but it’s different in each ear. A split hemisphere isochronic tones track works just the same. You hear two beats at the same time, not two tones as with binaural beats that create a single beat, but two different speeds of beats in each ear. This is what enables you to stimulate and influence each side of the brain with a different frequency of beat. Binaural beats can only stimulate and influence a whole brain effect using a single beat.

Alpha Waves (7-13hz) are associated with light meditation, peak performance, creativity and relaxed alertness. Your brain goes into this state naturally when you are daydreaming. Alpha waves also become more predominant when you close your eyes and relax your mind. This is the perfect state to be in for subliminal mind programming and enhancing your creativity.
There’s an aesthetic element to the music and there are a lot of drone-based sounds and time-stretched sounds, deep, rich bass sounds—there’s a spectrum of sounds within there—and what’s more, there’s a load of 3D processing that goes on to ensure that the mind doesn’t become habituated to them. There’s also a constant, subtle sense, a slow and gradual sense, of the sounds shifting around. And, there are layers of binaural beats.
For example, exercise and perusing a goal very ambitiously are both types of stress, except they ultimately benefit the body. Areas of the brain, including the hippocampus, amygdala and prefrontal cortex can pick up on positive stressful experiences and cause “stress-induced structural remodeling” of the brain, which means you experience alterations in behavioral and physiological responses to these positive events. The result is that in the future you’re better able to handle similar situations because you learn from them, associate them with a reward and stop perceiving them as threatening.
You may recognize the "binaural recording" from ASMR, where the technique is often used. This explains why, if you search for "binaural" on YouTube, you get a mixture of two entirely different kinds of results: binaural beats and binaural ASMR recordings. It gets especially confusing in that there's some questionable and/or unexplored science surrounding each one.
Move-Thru-It Strategy: to support optimum recovery rates, use 6-8 pumps or 3-4 droppers. Repeat every 1-3 hours for a day or two (with a good night's sleep). The idea here is a persistent frequency. Once you have achieved initial results, you can switch to more conventional usage patterns such as 3-4 times a day. For example: Kick-Ass Immune, Get Over It
Move-Thru-It Strategy: to support optimum recovery rates, use 6-8 pumps or 3-4 droppers. Repeat every 1-3 hours for a day or two (with a good night's sleep). The idea here is a persistent frequency. Once you have achieved initial results, you can switch to more conventional usage patterns such as 3-4 times a day. For example: Kick-Ass Immune, Get Over It
Just so, when you reach a state of meditation you don’t “keep digging”, so to speak. The hole has been dug. All that digging has done what it was meant to do. Once your technique has gotten you into meditation, STOP DIGGING! You’re there. If you keep digging you will frustrate your ability to remain in meditation for any significant period of time. Only resume your chosen technique if and when you slip out of the meditative state. If you’re human then you WILL slip out of that state again and again. Don’t worry about that. That’s how the process works for all of us mere mortals.
How does brainwave entrainment work? Consistent, precisely engineered audio frequencies in the form of binaural beats cause the brain’s frequencies to match the stimulus. Your brain perceives two beats with slightly different frequencies (which are inaudible to the ear) through your headphones. It takes the difference between the two, and matches its own frequency to it. This is called the “frequency following” response.
Start by kneading the muscles at the back of your neck and shoulders. Make a loose fist and drum swiftly up and down the sides and back of your neck. Next, use your thumbs to work tiny circles around the base of your skull. Slowly massage the rest of your scalp with your fingertips. Then tap your fingers against your scalp, moving from the front to the back and then over the sides.
“The great neuroscientist W. Gray Walter carried out a series of experiments in the late forties and fifties in which he used an electronic stroboscopic device in combination with EEG equipment to send rhythmic light flashes into the eyes of the subjects at frequencies ranging from ten to twenty five flashes per second. He was startled to find that the flickering seemed to alter the brain-wave activity of the whole cortex instead of just the areas associated with vision. Wrote Walter, “The rhythmic series of flashes appear to be breaking down some of the physiologic barriers between different regions of the brain. This means the stimulus of flicker received by the visual projection area of the cortex was breaking bounds— its ripples were overflowing into other areas.”
But the notion of changing brain waves is a very appealing one, from a marketing stand point. People can visualize brain waves and we like synchrony. Also, in the computer age, we understand the notion of “programming.” We also have been prepped for the future by movies such as The Matrix, where people could master Kung Fu in minutes by simply “downloading” the knowledge. This gives the whole notion a superficial plausibility. But the science just isn’t there.
Because the mind and body are a single system, changing our brainwaves and spending more time in harmonious, relaxed, and restorative mind-states also affects our physical health. Physical health then reinforces our mental-state, and a feedback loop of either positive or negative processes becomes established. Research studies have shown beneficial effects of using brainwave entrainment for treating migraine headaches, premenstrual syndrome, and for managing physical pain.

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Set aside time in your daily schedule. If possible, schedule a set time once or twice a day for your practice. If your schedule is already packed, remember that many relaxation techniques can be practiced while performing other tasks. Try meditating while commuting on the bus or train, taking a yoga or tai chi break at lunchtime, or practicing mindful walking while exercising your dog.
There’s a growing body of research suggesting that binaural beats can reduce different forms of anxiety, from mild to chronic. One especially interesting study looked at the effects of binaural beats on anxiety among patients preparing to undergo surgery—a life circumstance that is pretty anxiety provoking for most anyone. Over a period of six months, patients spent 30 minutes on the day of their surgery listening to binaural beats. Compared to patients who listened to a soundtrack that did not include binaural beats—and patients who received no “beats” therapy at all—the binaural beat listeners experienced significantly greater reductions in their anxiety levels.
Brainwave entrainment is a colloquialism for such 'neural entrainment', which is a term used to denote the way in which the aggregate frequency of oscillations produced by the synchronous electrical activity in ensembles of cortical neurons can adjust to synchronize with the periodic vibration of an external stimuli, such as a sustained acoustic frequency perceived as pitch, a regularly repeating pattern of intermittent sounds, perceived as rhythm, or of a regularly rhythmically intermittent flashing light.