The authors concluded that preliminary evidence suggested that brainwave entrapment was an effective therapeutic tool, but further research was required. The evidence presented appeared to justify the recommendation for further research. In view of the lack of controlled evidence and problems with methodology and reporting in the review, the authors’ conclusions regarding efficacy did not appear reliable.
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A more extensive study of over 100 participants who were undergoing general anesthesia for a day procedure, reported a decrease in pre-operative anxiety. The participants in this study listened to 30 minutes of binaural beats before surgery, but the researchers noted that people experiencing high levels of pre-operative anxiety could listen to binaural beats for up to 1 hour before anesthesia to reduce levels of anxiety.
Regarding split hemisphere isochronic tones. Think of this as two separate isochronic tones tracks playing independently of each other, one playing in one ear and the other one in the opposite ear. Better still, imagine someone playing and recording a drum beat at a rate of 5 taps per second (5Hz – 5 cycles per second). Then a separate recording of a drum beat is made at a rate of 10 taps per second (10 Hz). You then make an audio track where the left ear/channel hears the 5 drum beats recording and the right ear/channel hears the 10 beat recording. With headphones on, each ear can only hear each respective drum beat and not the other. So you are hearing two different beat recordings at the same time, but it’s different in each ear. A split hemisphere isochronic tones track works just the same. You hear two beats at the same time, not two tones as with binaural beats that create a single beat, but two different speeds of beats in each ear. This is what enables you to stimulate and influence each side of the brain with a different frequency of beat. Binaural beats can only stimulate and influence a whole brain effect using a single beat.
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These tones are similar in that they pulse like binaural beats. The difference is that they don’t need to be listened to using headphones as the pulse, or beat, is not generated by two different frequencies. The sound is an on/off pulse. Although you don’t need headphones to seperate the frequencies listened to, they are recommended. I’ve had just as much response to isochronic tones as I’ve had to binaural beats. I’d try both though, especially if you don’t respond to one or the other.
Both brainwave entrainment and neurofeedback deal with brainwaves, but the similarity stops there. Entrainment pushes your whole brain into a pre-determined state, while neurofeedback teaches you how to move specific parts of your brain on your own. It is the differeence between forcing the brain into a given position, and skills building so you can move it there yourself. 
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