Robert Monroe, a radio producer and executive published a popular book called Journeys Out of the Body about his out-of-body experiences when using brainwave entrainment. He later founded an original brainwave entrainment audio company, Hemi Sync. In 1981, the book Mega Brain by Michael Hutchison brought brainwave entrainment information, techniques, and terminology into the popular press.

What the Neuro Programmer does (as far as I can tell – access to much of the website requires the purchase of product) is present sound and visuals on the computer screen. The user is meant to passively view and listen to this while their brain is effortlessly programmed to solve whatever problem they are having or improve whatever performance they are interested in.

Entrainment is a phenomenon seen is a wide variety of different natural circumstance. In the field of chronobiology, the study of biological rhythms in living organisms, entrainment is the synchronization of a circadian rhythm with the rhythm of an external pattern, such as the synchronizing of women’s menstrual cycles with the phases of the moon or with one another in a group.
When you play a tone with a slightly different frequency into your left and right ear — say, 200 hertz (Hz) in one and 210 Hz in the other — they travel separately to your inferior colliculus, the part of your brain that gathers auditory input. There, the tones “squelch” together into a so-called “beat” at a perceived new frequency. (In this case, it would be 10 Hz.)
This research investigates the brainwave entrainment process and aims to demonstrate the usefulness of such an approach within the framework of cognitive performance improvements. In the introductory part the theories regarding the neurophysiological structure and the psychological processing of the cognitive system are discussed, for each of their components that are considered to be relevant for this research. The hypothesis states that the stimulation with binaural beats and stroboscopic light, synchronized at 10.2 Hz frequency, will produce a positive change in cognition. The research variables are the cognitive performance (the dependent variable) and the brainwave entrainment (the independent variable). The brainwave entrainment program consists in the synchronized application of Alpha binaural beats and stroboscopic light, at a 10.2 Hz frequency, in a 30 minutes long session. The difference was made by the stroop effect based exercise that was used as a frame. There were 60 participants, divided into two independent samples. The two independent samples t test for the means differences was used in the statistical analysis. The obtained results by evaluations and by statistics confirmed this research's hypothesis, stating that the stimulation with binaural beats and stroboscopic light, synchronized at 10.2 Hz frequency, will produce a positive change in cognition.

Once you begin to experience the beneficial aspects of brainwave entrainment, you may be tempted to have these tracks playing all the time during your waking and sleeping hours. This is NOT advisable, nor is it necessary. Remember, brainwave entrainment is exercise for your brain so your brain will need to rest and integrate the new changes that your entrainment regime is creating.

Most of all, don't feel bad if you fall asleep. Your brain is still receiving many of the benefits of entrainment while you sleep through the audio tracks. In fact, many people report better, more restful sleep when they use brainwave entrainment to help them fall asleep. However, I recommend that you do not go to sleep with your brainwave track set to repeat, as that can be too much stimulation for the brain.
From a strictly physical/emotional viewpoint, the benefits of meditation include (but are not limited to) such things as greater resistance to stress; less physical illness and improved resilience when illness does occur; better quality of sleep and increased recovery during sleep; a generally magnified sense of well-being; a sharper, clearer mind; increased capacity for learning; improved functioning in daily life; more harmonious relationships; greater control over emotional states, and more.
If anybody would like to look over the scientific evidence concerning brainwave entrainment and isochronic tones, I’ve done a lot of research over the years which I’ve collected at the PubMed website of NCBI – a branch of the National Institute of Health – that provides access to a large library of medical journal articles. I’ve made my list public so you can look through the journal articles that were published concerning this topic. Here’s the link: Most of the collection only gives access to abstracts or summaries unless you’re at some kind of educational institution that has a subscription to the particular journal that article is in, but I actually find abstracts really helpful. So have at it, read away. And if your psychiatrist/therapist thinks you’re nuts for feeling better after listening to isochronic tones, just whip out your 82-page collection of scientific journal abstracts written by her peers and give it to her to read. 🙂
Another consideration of stress is whether it is acute or chronic. “Acute stress” is what an individual experiences at the time the stressor is encountered (4). The stress response is activated, and the body returns to homeostasis once the challenge of the stressor is removed or the person successfully manages the situation. For example, an individual on the way to an important meeting gets into a traffic jam and realizes she is going to be late; the stress response starts. When she calls her boss and learns that she can conference into the meeting while on the road, the stress response subsides with the resolution of the situation. When an individual experiences acute stress on a consistent basis, such as with overcommitting at work or constant worrying, it is referred to as “acute episodic stress” (4). Individuals who experience acute episodic stress often show signs and symptoms of stress (Table 1) that can negatively impact physical and psychological health. These individuals can learn how to change behaviors and manage their stress to prevent these consequences.

Some studies have found that binaural beats can affect cognitive function positively or negatively, depending on the specific frequency that’s generated. For example, a study of long-term memory found that beta-frequency binaural beats improved memory, while theta-frequency binaural beats interfered with memory. This is something for scientists to continue to examine closely. For people who use binaural beats, it’s important to understand that different frequencies will produce different effects.
But the question is: Does it have a special effect on the brain? A lot of people think so. The basic claim being made for binaural beats is "resonant entrainment". Entrainment, in physics, is when two systems which oscillate at different frequencies independently are brought together, they synchronize with one another, at whatever the combined system's resonant frequency is. Examples of entrainment occur in animals in nature; for example the chirping of crickets or the croaking of frogs. Synchronization of menstrual cycles in women is another example. Even people coming together and dancing with one another is a type of entrainment. The basic claim for binaural beats is that the perceived low-frequency beat will entrain your brain wave pattern, thus forcing your brain into some desired state.

Isochronic tones work just the same in delta as they do in alpha, theta and beta and they are widely used in the brainwave entrainment community to help people sleep. Like you, I’ve also seen some websites saying they don’t work in delta, but it’s a bit like the game of Chinese Whispers, where someone makes a comment and then after it gets passed around and shared a lot the message gets distorted and appears to be a fact. I don’t know of any scientific reason why they wouldn’t work in delta. I remember some people talking about this on a brainwave entrainment forum many years ago. They were saying they found isochronic tones a bit too abrupt for using to help them sleep and they preferred binaural beats, as they thought they were a more soothing sound. That was just a personal preference shared by a couple of prominent forum members at the time and some people then took that as a fact for everyone. That’s where I think that belief originated from.

Transparent Corp's Research Area is arguably the most comprehensive resource for collated brainwave entrainment research.   Update: the main research area on Transparent Corp's website is currently being updated, so it is offline.  However, you can still access their peer-reviewed research paper as a PDF here: “A Comprehensive Review of the Psychological Effects of Brainwave Entrainment“.

Brainwave entrainment is a simple concept. It’s simply causing your brainwave frequency to align with some intended frequency in order to produce some intended result. It’s a way of modulating your brainwaves to resonate at a certain frequency. Being that there are certain dominant frequencies associated with different states of consciousness, this is being researched as a quick and effective way to induce states such as sleep, alertness, concentration, and even meditative and deep sleep states.
One RCT (n=108) showed significant reduction in anxiety from a single session of alpha/delta therapy for day surgery patients. A crossover RCT of a single session of theta stimulation in four healthy adults reported significant improvement from the intervention in one of five measures. Five pre/post studies reported significant benefit from the intervention for 16 of 27 outcomes.
At Gaia Meditation, most of audio programs including free relaxation music, free sleep music, free meditation music etc. use the technology of brainwave entrainment (or “brainwave synchronization”) with powerful binaural beats and isochronic tones. Our audio tracks utilize pure and precisely tuned sound frequencies which will drive your brain activity (consciousness) into your desired state: Gamma, Beta, Alpha, Theta or Delta.
Brainwaves, or neural oscillations, share the fundamental constituents with acoustic and optical waves, including frequency, amplitude and periodicity. Consequently, Huygens' discovery precipitated inquiry[citation needed] into whether or not the synchronous electrical activity of cortical neural ensembles might not only alter in response to external acoustic or optical stimuli but also entrain or synchronize their frequency to that of a specific stimulus.[16][17][18][19]