Controlled or pre/post studies of the effects of BWE using auditory or visual stimulation were eligible for inclusion, provided pulses of light or tone were delivered at frequencies hypothesised to have a beneficial effect or in line with a protocol addressing clinical outcomes. Studies were required to report clinical or psychological outcomes (measured using standard methods or as deemed appropriate by peer review) and to report statistical analysis. Studies of outcomes such as electroencephalogram (EEG) response or neurotransmitter levels were not eligible. Case studies were excluded.

Thanks for the reply. I am now clearer on ‘what’ is heard. Can you expand or point me in direction ..a bit more about ‘pitch frequency’ and frequency spoken about and what exactly is the difference ..and how we use the higher pitch frequencies to ‘hear’ or become aware of them? Would you only pick up the low freq on a EEG?. sorry for being pedantic still does not clear up split isochronics and possibly creating same situation as binaural beats..
Rudy's primary work is on Alzheimer's. In this disease, beta amyloid proteins form plaques in the brain and kill nerve cells eventually leading to dementia. Research from Washington University School of Medicine in St. Louis shows that when people's brains are in a Delta brain wave state, beta amyloid production in the brain ceases and the toxic material is cleared away. One thought is to explore the possibility of using brain entrainment technology to help treat Alzheimer's, but at this point all it is being used for is to help people meditate, relax and dream instantly and effortlessly.
Delta is the lowest frequency range of .2Hz - 3Hz, corresponding to dreamless sleep, growth hormone release, healing and ultra deep trance. Effective in reducing migraines, chronic pain and blood pressure. By inducing a predominantly Delta state in the brain while remaining awake, you push your brain to operate in a truly unique state that literally forces greater neural adaptation and cross-connection between the regions of your brain.

Another very useful application for the Theta & Delta frequencies is to keep your eyes open while listening to the entrainment recordings. Simply pick a spot on the wall and look beyond it as if you were looking at the view beyond the wall. Keeping your eyes open while in Theta and Delta brainwave states stimulates connections between the visual information processing centers of your brain and the "dream vision" centers that normally only function with the eyes closed.

Sound and light are the most popular methods to entrain the mind, yet there are a few other options in our toolbox. Using vibrational energy from sources such as magnets and electricity has been proven to help overcome addictions, depression, and even treat neurological disorders such as Parkinson’s. In this section, we cover these alternative forms of brainwave entrainment.

From a strictly physical/emotional viewpoint, the benefits of meditation include (but are not limited to) such things as greater resistance to stress; less physical illness and improved resilience when illness does occur; better quality of sleep and increased recovery during sleep; a generally magnified sense of well-being; a sharper, clearer mind; increased capacity for learning; improved functioning in daily life; more harmonious relationships; greater control over emotional states, and more.
Research: the authors stated that qualitative electroencephalogram signatures needed to be developed for different disorders and tested using standard validated methods of psychological assessment. Larger RCTs were needed with clear inclusion criteria for participants. The RCTs should measure qualitative EEG, hormone levels and the time of day of the intervention. Interventions protocols should be clearly defined and the relationship between session frequency/ duration and outcomes should be explored. More studies of auditory stimulation were needed, as well as studies comparing different types of stimulation, monaural, binaural and isochronic beats and use of white noise versus music.
Just as stress can increase the risk for chronic diseases and other health problems, dealing with chronic conditions and poor health can increase the amount of stress one experiences. Stress also influences behaviors that affect health. Diet choices, sleep habits, and drug use are behaviors that are often negatively affected by stress (3). The APA’s 2011 survey showed that 39% percent of respondents reported overeating or eating unhealthy food because of stress, and 29% reported skipping a meal (3). In addition, 44% reported lying awake at night because of stress (3). On a positive note, 47% of respondents reported walking or exercise as a way of managing stress (3).
A binaureal beat is created by playing a different tone in each ear, and the interference pattern between the slightly differing frequencies creates the illusion of a beat. It's intended to be heard through headphones, so there's no cross-channel bleed across both ears. Listen to this, I'll play a simple binaural beat, and I'll slide the pan control back and forth from one ear to the other. You can see that there isn't actually any beat, it's just an acoustic illusion:
This simple app doesn’t have tons of bells and whistles, but by being just a one-screen app it doesn’t drain your battery or interfere with other apps you might be running. The interface is straightforward and lets you input exactly what binaural beats frequency you want to achieve. This is a great app if you know exactly what you want and you don’t want anything to get in the way of that.
Binaural beats were the first method discovered for brainwave entrainment and works by delivering tones of different audible frequencies to the two ears with the difference in frequency between the two tones being the frequency of entrainment. The difference in frequency between the two tones must be less than 30 hertz, and this resulting frequency is called a beat or the target frequency, and it is processed in a brain region called the olivary body. When listening to such tones with stereo headphones, the two hemispheres of the brain become synchronized at the target frequency.

There’s also some new stuff I’ve certainly never included in tracks before including some gentle pink noise and brown noise blended together in the background with what’s called phase modulation. This is almost outside of awareness as you’re listening to it. This is how your ear tells what direction a sound is coming from. Does it arrive at your left ear slightly before your right ear? You can modulate that. So, again, it has a very gentle, imperceptible rhythmic quality to it.
All of this is entirely understandable, even somewhat predictable. Unfortunately, it quickly becomes counter-productive. Such experiences, while having a certain feeling of solidity to them, are largely the product of our desires and expectations. Did your face get flushed? One look in the mirror confirms it did. Was this caused by the entrainment? No, it was not. It was the result of what was sought after and what was expected or even hoped for.

“Like the pulses of vibration that produce sound on a guitar string, your brain also creates pulses of vibrations. These vibrations are electrical impulses,” continues Naik. “Their activity can be measured by using an EEG (electroencephalogram), which measures the frequency of these pulses [which is measured in Hertz]. Your brain actually has a predominant frequency at which it operates in any given moment; this can be associated with your state of mind.”
“Stress” is a commonly used term, and it is often used with different meanings. The standard definition for stress that will be used in this article is the disruption of the body’s homeostasis or a state of disharmony in response to a real or perceived threat or challenge (8). The threatening or challenging situation is referred to as a “stressor.” When a person encounters a stressor, the body prepares to respond to the challenge or threat. The autonomic nervous and endocrine systems respond by producing the hormones epinephrine, norepinephrine, and cortisol. The result of this hormone production is a cascade of physiological reactions that make up the stress response. Epinephrine and norepinephrine are involved in the initial changes that take place to prepare the body to react and to prepare for a challenge. These responses include increases in heart and respiration rates, blood pressure, perspiration, and energy production (8). There also is a suppression of immune function, production of β-endorphin (the body’s natural pain killer), and increased acuity of the senses. These changes make up the fight-or-flight response, which prepares the body to cope with the stressor. If the stressor is perceived as negative or more as a threat than as a challenge, cortisol production is increased. Cortisol is involved in energy production but also suppresses immune function.

“Stress and sleepless nights are closely linked,” Buenaver says. “If you’re in pain, tend to worry, or are coping with a difficult situation in your life, you may have more stress hormones than usual circulating in your body. A poor night’s sleep adds even more. And those hormones may never be fully broken down. It’s like running an engine in fifth gear all the time.”

In physics, entrainment is the process of two oscillating systems coming to assume the same periodic rhythm, such as is observed when two clocks slowly synchronize their ticking and tick together in harmony after some time. Pendulums also achieve this same synchronicity when swinging in close proximity to one another, a phenomenon first observed and written about in 1665 by Christiaan Huygens, a Dutch scientist.

Brainwave entrainment is a method which utilizes frequencies of the brain in order to bring about specific desired thoughts and behavior. In other words, brainwave entrainment is used to induce different brainwave states related to: enhanced focus, relaxation, sleep induction, meditation, etc. With the help of a specific stimulus, aural (audio), photic (visual) or the combination of the two, we naturally induce the brain to respond by synchronizing with the stimulus frequency; this is called the “frequency following response”. The assumption is that the human brain has a tendency to change its dominant Electroencephalography frequency (recording of electrical activity along the scalp) towards the frequency of a dominant external stimulus. This is why we also talk about “brainwave synchronization”.
Subsequently, the term 'entrainment' has been used to describe a shared tendency of many physical and biological systems to synchronize their periodicity and rhythm through interaction. This tendency has been identified as specifically pertinent to the study of sound and music generally, and acoustic rhythms specifically. The most ubiquitous and familiar examples of neuromotor entrainment to acoustic stimuli is observable in spontaneous foot or finger tapping to the rhythmic beat of a song.